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Pathogens, Vaccines & Immunity

Labs associated with

Avci Lab focuses on mechanisms of immune activation by carbohydrate antigens; design and development of knowledge-based vaccines and therapeutics against pathogens and cancers.

Antigenic variation in African trypanosomes

Among the parasites we currently study in the laboratory are African trypanosomes, unicellular eukaryotic protozoa that infect the bloodstream of mammals to cause sleeping sickness in equatorial Africa. Trypanosomiasis continues to be a daily…

We study CRISPR-Cas immune systems that protect prokaryotes from viruses and provide research tools for important biotechnology and biomedical applications

CRISPR-Cas systems are recently discovered RNA-based adaptive immune systems that control invasions of viruses and other mobile…

Research in the Woods group examines the relationship between carbohydrate conformation and biological recognition. Areas of particular interest include carbohydrate antigenicity in immunological events, carbohydrate- processing enzymes, and the development of appropriate simulational methods…

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