The BFF has broad range capabilities in fermentation, cell culture, monoclonal antibody generation and protein purification. Watch this short video for an overview. Endotoxin Testing The BFF endotoxin services can provide fast, economical, and reliable measurements for your important reagents and products. Animal Cell Culture BFF staff have experience with a wide range of cell types and are familiar with production using stable cell lines or transient transfection. Biosafety Level 2+ Fermentations The BFF now has fermentation equipment housed in the UGA Animal Health Research Center (AHRC) capable of fermenting organisms that are considered BSL2. Volumes are up to 60L per run, earning the "plus" designation. Fermentation BFF has experience with a wide range of organisms including bacteria, yeast, and fungi. Our pilot plant can support production of cultures up to 750L with full downstream processing capabilities. Molecular biology BFF staff have experience with construct design and can assist in gene synthesis (commercial provider). Monoclonal Antibodies The BFF offers monoclonal and polyclonal antibody discovery services. These services include immunizing mice, performing fusions, cloning selected cell lines, preserving these selected cell lines in liquid nitrogen, and producing and purifying antibodies from cell cultures. Process BFF staff have experience in batch, fed-batch, and continuous culture process development. Fermentation equipment has full on-line process control and on-line data logging. Protein Purification BFF has a deep knowledge base in protein purification with experience in a variety of purification modalities.
